Tranquilene Total Calm®
Tranquilene Total Calm®
Tranquilene Total Calm®
Tranquilene Total Calm®
Tranquilene Total Calm®

Tranquilene Total Calm®

Natural Stress and Anxiety Supplement

A comprehensive natural anti-anxiety supplement designed to correct stress-causing nutritional imbalances over time while providing immediate herbal calming. Get fast anxiety relief, long term mood, and daily stress support with this all natural and non habit-forming unique botanical blend. Our formulated serotonin and GABA works with your body for long term mood support for an overall improved quality of life. Try it today!

Sale price $42.50 Save $-42.50

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Customer Reviews

Based on 633 reviews
Natalie Hill

Tranquilene is an essential addition to our daughter's therapy. It effectively grounds/calms her especially before musicial performances.


The best product out there for anxiety, panic attacks. All natural and no sides effects while taking with others medications.

Late delivery

I depend on this supplement as it makes a huge difference with my chemistry. Normally I buy on Amazon but this time bought three bottles in the Tranquility site. Unfortunately the delivery took much longer than Amazon which can be the next day. This was more like 10 days so I had to buy more on Amazon in the interim to get me through. Sales are good but just know it takes much longer to receive even though you pay for shipping!

Solution to My anxiety Doctors could not fix

February 20, 2024 A few years ago I was struggling with anxiety and depression. I had adult children with Drug Addictions who were the root problems. I was unable to focus. Searching for something to help my daughter, I found Tranquilene. Researching the ingredients, their properties and deciding it would be safe to take and worth the chance it would work. My daughter said it didn't help, so I took it myself. I had been seeing my doctor who prescribed three different medications, that didn't work for my anxiety or depression. To my amazement...I noticed the first day a difference in my mental state. This supplement doesn't work like say zanax or zoloft, or some of the others. You don't get that immediate calming affect (or high if you will). No this was different. I was focusing and able to get a grip. I took this med for the recommended 3-months. That was almost 8 years ago and I have never had that anxiety or depression since. And...I didn't have to continue taking it to stay on top of my mental stability. I do recommend Tranquilene Calm if you are experiencing anxiety or depression.


I have struggled with depression for as long as I can remember, I'm 46 years old now, so most of my life...I have been on various antidepressants over the years, but never really found one that treated the cause. I have been taking Tranquiline Total CALM every day now for over 3 years and I can honestly say, I could not function without it!!! I sometimes forget I even have depression, it works so well - thank you SO much, Tranquiline CALM, you've truly been a lifesaver!!!:)








Tranquilene® is an all-natural supplement designed to provide FAST anxiety relief, long-term mood support and everyday stress control. Our clinically proven ingredients combine the best in western science with the most effective in eastern herbal medicine, bringing you the safest, most potent formula on the market.

Tranquilene® works daily to keep you calmer and nutritionally equipped to handle the stresses of life.† Tranquilene’s unique formula brings together the best of western science with some of the Eastern world’s most effective herbal mood-balancing remedies for a safe and effective natural anti-anxiety formula.

While our calming botanical blend works to quickly bring down that panicky feeling, our scientifically-formulated Serotonin and GABA support system works with your body to build long-term mood support. And unlike many of the hard drugs pharmaceutical companies push, Tranquilene® is all-natural and non habit-forming.


Your Peace of Mind Shield

Immediate Relief

FAST Relief For Panic and Anxiety

Long-Term Mood Support System


A Natural Way of Life

ALL NATURAL Ingredients

Unsurpassed Value and Quality


Easy Everyday Mood Support

Lifestyle Convenience

Explore The Ingredients





Passion Flower

Brahmi (Bacopa Monnieri)


B Complex

Vitamin D


Saftey Information

Tranquilene® is safe, natural and usually well tolerated by the body. Most people who take Tranquilene® do not experience side effects. When side effects do occur, they tend to be mild and short-lasting.You can safely take Tranquilene® with all nutritional supplements and most prescription medications.Please consult a physician before taking Tranquilene® if you are pregnant or nursing.Recommended dosage is two capsules taken with water, either both in the morning, or one in the morning and one in the afternoon – as you see fit. It is not recommended that you exceed three capsules at a time or four in one day. Exceeding the maximum dosage is not dangerous, though it may lead to excessive drowsiness.When taken as directed, Tranquilene® is safe and poses no short-term or long-term health risks.

Drug Interactions

Please talk to your doctor before taking Tranquilene® with blood thinners, muscle relaxants, other sleep or anxiety medicines, pain medicines, seizure medicines, or other medicines that cause drowsiness. Tranquilene® may increase the sedative effects of these drugs.Do not consume excessive quantities of alcohol while taking Tranquilene®. Tranquilene® may increase the sedative effects of alcohol.Do not take Tranquilene® if you are currently taking an MAOI or have taken an MAOI within the past two weeks.

Possible Side Effects

While most people taking Tranquilene® experience NO side effects, possible side effects can include: Drowsiness, Fatigue, Stomach upset, Headache, Morning grogginess (if taken before bed), Increased effects of sedative drugs, Lowering of blood pressure.

Feel free to contact Tranquilene® Customer Support if you have any questions or concerns.

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